{"created":"2023-06-19T11:18:04.462886+00:00","id":32,"links":{},"metadata":{"_buckets":{"deposit":"9e135c64-a96a-4832-8701-cddbd1857e8b"},"_deposit":{"created_by":3,"id":"32","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"32"},"status":"published"},"_oai":{"id":"oai:kinran.repo.nii.ac.jp:00000032","sets":["11:12:14"]},"author_link":["46","43","45","44"],"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"83","bibliographicPageStart":"77","bibliographicVolumeNumber":"2","bibliographic_titles":[{}]}]},"item_3_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"ウリカーゼ・ペルオキシダーゼ (POD) 系からなる尿酸測定試薬を用いて、濃度の異なる2種類の尿標品の尿酸値を測定した結果、高濃度の尿の方が低濃度よりも低い尿酸値を示した。この原因について検討したところ、次の結果を得た。(1) 尿酸値は尿の希釈濃度が0～約20%までは濃度に依存して上昇したが、さらに尿の濃度を増加すると逆に低下した。この低下作用は、尿を121℃、15分間加熱した場合には発現されなかった。(2) 希釈した尿 (希釈尿) に、各種の方法で処理した尿を加えた場合、尿酸値の低下がみられた。(3) 希釈尿に尿酸を添加したところ、尿酸の濃度に伴い尿酸値は上昇した。(4) 一定量の尿酸に処理した尿を加えた場合、尿酸値の低下がみられ、この尿を90℃で15分間放置しても低下作用は消失しなかった。以上の結果から、ウリカーゼおよびPOD反応の阻害因子が尿中に存在し、この因子が尿酸の分解ならびにPOD反応を抑制し、尿中の尿酸測定値の低下を引き起こすと推察される。","subitem_description_type":"Other"}]},"item_3_description_15":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_description":"13","subitem_description_type":"Other"}]},"item_3_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00004186759","subitem_description_type":"Other"}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA12002610","subitem_source_identifier_type":"NCID"}]},"item_3_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"千里金蘭大学 生活科学部 "},{"subitem_text_value":" 千里金蘭大学 生活科学部"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"福田, 典子"},{"creatorName":"フクダ, ノリコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"43","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山下 義昭"},{"creatorName":"ヤマシタ, ヨシアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"44","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuda, Noriko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"45","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamashita Yoshiaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"46","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-25"}],"displaytype":"detail","filename":"KJ00004186759.pdf","filesize":[{"value":"447.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00004186759.pdf","url":"https://kinran.repo.nii.ac.jp/record/32/files/KJ00004186759.pdf"},"version_id":"d83f1f1d-5e74-45e2-b589-1b1471904dcc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"尿酸 ","subitem_subject_scheme":"Other"},{"subitem_subject":" 尿 ","subitem_subject_scheme":"Other"},{"subitem_subject":" ウリカーゼ ","subitem_subject_scheme":"Other"},{"subitem_subject":" ペルオキシダーゼ ","subitem_subject_scheme":"Other"},{"subitem_subject":" 尿酸値低下作用","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"尿酸値の測定に影響を与える尿中低分子物質","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"尿酸値の測定に影響を与える尿中低分子物質"},{"subitem_title":"Urinary Low-Molecular Inhibitor on Determination of Uric Acid Amount","subitem_title_language":"en"}]},"item_type_id":"3","owner":"3","path":["14"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-10-28"},"publish_date":"2005-10-28","publish_status":"0","recid":"32","relation_version_is_last":true,"title":["尿酸値の測定に影響を与える尿中低分子物質"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T11:26:49.761058+00:00"}